谷春雨

谷春雨

副主任医师 / 无

挂 号 费:60元 (北京医保20元)


出诊时间:周四上午


专业特长:胶质瘤干细胞及颅底肿瘤相关的基础及临床研究


个人简历

神经外科博士,留美博士后,副主任医师,1999于中国医科大学获临床医学学士学位;2003年于中国医科大学获神经外科硕士学位; 同年于中国医科大学附属盛京医院神经外科工作,2005年留学日本就读于日本浜松医科大学神经外科,2010年获得医学博士学位。同年留学美国俄亥俄州立大学医学院神经外科做博士后研究工作。2012年回国,在首都医科大学三博脑科医院神经外科颅底肿瘤病区工作至今。长期从事神经系统脑肿瘤的临床和研究工作,在脑肿瘤诊断、手术治疗方面有丰富的临床经验。

代表性文章

1.Liu H, Sun Q, Sun Y, Zhang J, Yuan H, Pang S, Qi X, Wang H, Zhang M, Zhang H, Yu C, Gu C:MELK and EZH2 Cooperate to Regulate Medulloblastoma Cancer Stem-like Cell Proliferation and Differentiation. Mol Cancer Res. 2017 Sep;15(9):1275-1286

2. Zhang M, Wang Z, Zhang J, Zhang H, Gu C, Wang H, Yu C, Wu H:Metastases in cerebellopontine angle from the tumors of central nerve system. J Clin Neurosci. 2017 Aug;42:84-90

3. Kim SH, Joshi K, Ezhilarasan R, Myers TR, Siu J, Gu C, Nakano-Okuno M, Taylor D, Minata M, Sulman EP, Lee J, Bhat KP, Salcini AE, Nakano I: EZH2 protects glioma stem cells from radiation-induced cell death in a MELK/FOXM1-dependent manner. Stem Cell Reports. 2015 Feb 10;4(2):226-38

4. Minata M, Gu C, Joshi K, Nakano-Okuno M, Hong C, Nguyen CH, Kornblum HI, Molla A, Nakano I: Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition. PLoS One. 2014 Apr 16;9(4):e92546

5. Gu C, Banasavadi-Siddegowda YK, Joshi K, Nakamura Y, Kurt H, Gupta S, Nakano I: Tumor-Specific Activation of the C-JUN/MELK Pathway Regulates Glioma Stem Cell Growth in a p53-Dependent Manner. Stem Cell. 2013 May;31(5):870-81

6. Li S, Gu C, Gao Y, Amano S, Koizumi S, Tokuyama T, Namba H: Bystander effect in glioma suicide gene therapy using bone marrow stromal cells. Stem Cell Res. 2012 Nov;9(3):270-6

7. Gu C, Yokota N, Gao Y, Amano S, Koizumi S, Tokuyama T, Namba H: Targeting therapy against promyelocytic leukemia gene using arsenic acids in experimental intracranial medulloblastoma. Neurologia medico-chirurgica, 2012;52(2):62-7

8. Amano S, Gu C, Koizumi S, Tokuyama T, Namba H: Tumoricidal bystander effect in the suicide gene therapy using mesenchymal stem cells does not injure normal brain tissues. Cancer Lett. 2011 Jul 1;306(1):99-105

9. Amano S, Gu C, Koizumi S, Tokuyama T, Namba H:Timing of ganciclovir administration in glioma gene therapy using HSVtk gene-transduced mesenchymal stem cells. Cancer Genomics Proteomics. 2011 Sep-Oct;8(5):245-50

10. Koizumi S, Gu C, Amano S, Yamamoto S, Ihara H, Tokuyama T, Namba H:Migration of mouse-induced pluripotent stem cells to glioma-conditioned medium is mediated by tumor-associated specific growth factors. Oncol Lett. 2011 Mar;2(2):283-288

11. Gu C, Yokota N, Gao Y, Yamamoto J, Tokuyama T, Namba H: Gene expression of growth signaling pathways is up-regulated in CD133-positive medulloblastoma cells. Oncol Lett. 2011 Mar;2(2):357-361

12. Gao Y, Gu C, Li S, Tokuyama T, Yokota N, Nakayama KI, Kitagawa M, Namba H:p27 modulates tropism of mesenchymal stem cells toward brain tumors. Exp Ther Med. 2010 Jul;1(4):695-699

13. Gu C, Li S, Tokuyama T, Yokota N, Namba H: Therapeutic effect of genetically engineered mesenchymal stem cells in rat experimental leptomeningeal glioma model. Cancer Lett. 291: 256–262, 2010

14. Amano S, Li S, Gu C, Gao Y, Koizumi S, Yamamoto S, Terakawa S, Namba H: Tumoricidal bystander effect-mediated suicide gene therapy of glioma using genetically engineered bone marrow-drived mesenchymal stem cells. Int J Oncol. 35: 1265-1270, 2009


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